We are interested in developing mass spectrometry methods to study biomolecular systems, especially those which are challenging to study with conventional methods. This includes intrinsically disordered proteins, protein-nucleic acid, protein-protein and protein-drug complexes and ternary complexes formed by PROTACs and molecular glues. Overall, we aim to delineate the structure and dynamics of these systems to better understand their roles in biology.
Biomolecular Mass Spectrometry At The University Of Strathclyde
What we’ve been up to recently
Conformational landscapes resolved by ion mobility mass spectrometry reveal mechanisms of polyubiquitin-controlled phase separation
Every cell in your body faces a constant challenge: keeping itself healthy. Damaged, misfolded, or excess proteins must be identified and cleared away before they…
Working With Us
Not only is the group nice to work in, and the research fun and important but being situated in Glasgow City Centre in Scotland also has many advantages!
Recent Projects
Conformational landscapes resolved by ion mobility mass spectrometry reveal mechanisms of polyubiquitin-controlled phase separation
Every cell in your body faces a constant challenge: keeping itself healthy. Damaged, misfolded, or excess proteins must be identified and cleared away before they…
Ion mobility mass spectrometry unveils conformational effects of drug lead EPI-001 on the intrinsically disordered N-terminal domain of the Androgen Receptor
Protein - You may know it as a morning protein shake or your essential gym friend, but did you also know that a lot of…
