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Biomolecular Mass Spectrometry At The University Of Strathclyde

We are interested in developing mass spectrometry methods to study biomolecular systems, especially those which are challenging to study with conventional methods. This includes intrinsically disordered proteins, protein-nucleic acid, protein-protein and protein-drug complexes and ternary complexes formed by PROTACs and molecular glues. Overall, we aim to delineate the structure and dynamics of these systems to better understand their roles in biology.

Meet Our Team

What we’ve been up to recently

General News

Cara presents to the Chemical Biology and Medicinal Chemistry Section

Cara presented a talk titled "Using Native Mass Spectrometry to Investigate Complexes Formed by Protein Degraders" to the Chemical Biology and Medicinal Chemistry section of…
General News

Sarah and Kirsten Complete their Master’s Projects

After the successful completion of their theses, presentations, and vivas, Sarah and Kirsten's master’s projects within the group have come to an end. Congratulations to…
Conferences

Cara Attends STEM for BRITAIN 2025

Cara was selected as a finalist in STEM for BRITAIN 2025, the annual major scientific poster competition and exhibition which has been held in Parliament…
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Working With Us

Not only is the group nice to work in, and the research fun and important but being situated in Glasgow City Centre in Scotland also has many advantages!

Work With Us

Recent Projects

Highlights

Ion mobility mass spectrometry unveils conformational effects of drug lead EPI-001 on the intrinsically disordered N-terminal domain of the Androgen Receptor

Protein - You may know it as a morning protein shake or your essential gym friend, but did you also know that a lot of…
Highlights

Cancerous Proteins Find Themselves in a Sticky Situation – Using Native Mass Spectrometry to Investigate Molecular Glue Ternary Complexes

Molecular glues are a new class of drug which, as the name suggests, “stick” proteins together. They do this to bring proteins called E3 ligases…
Highlights

Ion mobility reveals protein shape changes in conditions that favour droplet formation

The aim of this project was to better understand the shapes and behaviour of a protein called UBQLN-2. This is a protein involved in Amyotrophic…
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