HighlightsPublications Ion mobility mass spectrometry unveils conformational effects of drug lead EPI-001 on the intrinsically disordered N-terminal domain of the Androgen Receptor Protein - You may know it as a morning protein shake or your essential gym friend, but did you also know that a lot of…IkhlasApril 29, 2024
HighlightsPublications Cancerous Proteins Find Themselves in a Sticky Situation – Using Native Mass Spectrometry to Investigate Molecular Glue Ternary Complexes Molecular glues are a new class of drug which, as the name suggests, “stick” proteins together. They do this to bring proteins called E3 ligases…CaraJanuary 25, 2024
HighlightsPublications Ion mobility reveals protein shape changes in conditions that favour droplet formation The aim of this project was to better understand the shapes and behaviour of a protein called UBQLN-2. This is a protein involved in Amyotrophic…BexNovember 23, 2023